C-C motif chemokine ligand 5 and C-C chemokine receptor type 5: possible diagnostic application in breast cancer patients
نویسندگان
چکیده
منابع مشابه
CCR1 (chemokine (C-C motif) receptor 1)
Note CCR1, a member of the beta chemokine receptor family, is a seven transmembrane protein similar to G protein-coupled receptors. CCR1 is the first human CC chemokine receptor to be identified at the cDNA level. It has a functional viral homolog, US28, which is a human cytomegalovirus.The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on acti...
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Review on CXCL17, with data on DNA/RNA, on the protein encoded and where the gene is implicated.
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N-terminal modifications of the chemokine RANTES bind to C-C chemokine receptor 5 (CCR5) and block human immunodeficiency virus type 1 (HIV-1) infection with greater efficacy than native RANTES. Modified RANTES compounds induce rapid CCR5 internalization and much slower receptor reexpression than native RANTES, suggesting that receptor sequestration is one mode of anti-HIV activity. The rates o...
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Chemokine (C-X-C motif) receptor 4 (CXCR4) has been found to closely correlate with the incidence, development, treatment and prognosis of breast cancer. The aim of the present study was to investigate the effects of CXCR4 on bone metastasis in breast cancer and to explore the mechanisms of this process. CXCR4 small interfering RNA was transfected into the breast cancer cell line, MDA-MB-231BA-...
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Other names: CD182; CD183; CKR-L2; CMKAR3; CXC-R3; CXCR-3; GPR9; IP10; IP10-R; Mig-R; MigR HGNC (Hugo): CXCR3 Location: Xq13.1 Note: CXCR3 is a G protein-coupled receptor with selectivity for three chemokines, termed IP10 (CXCL10), Mig (CXCL9) and I-TAC (CXCL11). IP10, Mig and I-TAC belong to the structural subfamily of CXC chemokines, in which a single amino acid residue separates the first tw...
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ژورنال
عنوان ژورنال: Acta Biochimica Polonica
سال: 2020
ISSN: 1734-154X,0001-527X
DOI: 10.18388/abp.2020_5402